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Lisa Heather is an Associate Professor in the Department of Physiology, Anatomy, and Genetics at the University of Oxford. Her research revolves around understanding metabolism in the heart and the consequences when it goes awry. Her passion for metabolism began during her undergraduate degree in Medical Biochemistry at the University of Surrey, where she appreciated how everything fits together like a complex jigsaw, resembling a public transport network. If there is a malfunction in an enzyme pathway, the entire system can come to a halt. Her doctoral research investigated the role of abnormal substrate metabolism in the development of cardiac hypertrophy. Following her PhD, her post-doctoral research focused on mitochondrial metabolism and its role in the progression of cardiac diseases. In 2011, she was awarded the Diabetes UK RD Lawrence Fellowship to study the role of hypoxia in metabolism within the type 2 diabetic heart, a critical area since cardiac disease is the leading cause of mortality in type 2 diabetes patients. In 2018, she received the British Heart Foundation Intermediate Fellowship to investigate why fat accumulation in the heart of type 2 diabetics is detrimental, studying the signaling pathways of fatty acids that contribute to cardiomyocyte dysfunction in response to stress.
Department of Politics and International Relations - Higher Level English requirement.