Dr. Luay Joudeh

Biography

Luay Joudeh is an interdisciplinary scientist with deep expertise in biochemistry, biophysics, and advanced microscopy. His research spans molecular mechanisms of DNA replication and repair, along with the development and application of cutting-edge imaging technologies to interrogate biological processes at high resolution. With a strong foundation in single-molecule imaging, Luay has developed and applied a wide range of techniques including Förster Resonance Energy Transfer (FRET), single-particle tracking, super-resolution microscopy, and optical tweezers-based confocal microscopy. He has pioneered applications of label-free force spectroscopy to study molecular interactions and conformational dynamics in real-time. In recent years, Luay has expanded his expertise into cryo-electron microscopy (cryo-EM), specifically single-particle analysis, and is currently leading the establishment of cryo-confocal correlative imaging workflows at the University of Cambridge. His goal is to integrate approaches such as cryo-electron tomography (cryo-ET) for 3D cellular imaging, enabling high-resolution structural insights into pathogen-host interactions and intracellular architecture. Luay is also a strong advocate for methodological innovation and cross-disciplinary collaboration, currently managing the Pathogen Cryo-Imaging Facility to assist researchers in the biological sciences with advanced cryogenic imaging platforms.

Research Interests

Experience