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At the Thorne Lab, we study the interactions of emerging viruses with the innate immune system, focusing on understanding how viruses manage to overcome this system to infect and contribute to virus transmission and pandemic potential. The key question we ask is: what makes pandemic viruses special? My research includes revealing novel opportunities for therapeutic intervention to limit virus replication and inflammation, using viruses as tools to uncover new knowledge in cell biology and innate immune regulation. I joined Imperial College London in 2023 as an Assistant Professor of Molecular Virology to establish my research group. My career has included utilizing viruses as discovery tools to study virus-host interactions, with a PhD from Imperial and postdoctoral research at the University of Cambridge, where I characterized host factors important in norovirus infection. A significant part of my work has involved responding to the Ebola virus outbreak in Sierra Leone, and I further pivoted my research in response to SARS-CoV-2, combining my expertise in RNA virology and innate immunology to help in outbreak containment. Public engagement is a central part of my research ethos, and I have created the Infectious Science program to stimulate interest in infectious diseases among school children through interactive activities. My goal is to empower participants with knowledge about how infectious diseases spread and how we can take action to protect our communities.
Imperial College London • London, United Kingdom
Leading research in molecular virology, focusing on the interactions between emerging viruses and the innate immune system.
Specialisms available in Materials for the Energy Transition or Theory and Simulation of Materials.