Dr. Luisa Escobar Hoyos

Biography

Luisa Escobar-Hoyos obtained her master’s degree in Biomedical Sciences from Universidad del Valle in Cali, Colombia. She was a Fulbright Scholar and pursued her Ph.D. in Cancer Molecular Cellular Pharmacology at Stony Brook University, where she was mentored by Dr. Kenneth Shroyer. Following her Ph.D., she completed postdoctoral training at Memorial Sloan Kettering Cancer Center under the mentorship of Drs. Steven Leach and Omar Abdel-Wahab. In 2020, she joined the Department of Therapeutic Radiology at Yale University as an Assistant Professor. Her research focuses on understanding somatic mutations and aberrant RNA processing in tumors, particularly pancreatic and lung cancers, with the aim of developing novel therapeutic strategies. Her work includes research on RNA splicing and its implications in cancer treatment, specifically targeting KRAS and p53 mutations. She has proposed a novel therapy called Splicing-Hit Oligonucleotide Therapy (SHOT), which aims to correct RNA splicing errors to selectively kill cancer cells. Collaborating with various laboratories, she seeks to develop efficient therapies that could ultimately lead to cures for aggressive malignancies.

Research Interests

Experience

Awards