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Lynne Howell is a prominent researcher in the field of microbial pathogenesis and structural biology. Her investigative work primarily focuses on understanding the molecular and cellular processes that underlie microbial infections, particularly those involving biofilms. Biofilms are complex communities of microorganisms that adhere to surfaces and are encased in a protective matrix. Howell's research has identified glycosyl hydrolases that can prevent biofilm formation and degrade preformed biofilms, presenting opportunities for novel therapeutic strategies against bacterial and fungal infections. She employs a multidisciplinary approach that combines microbiological studies with structural biology and biochemical techniques to explore crucial components of biofilms, such as exopolysaccharides and type IV pili, which are integral to microbial virulence. Howell's work contributes significantly to understanding antibiotic tolerance and the challenges posed by chronic bacterial infections, with implications for healthcare systems. She holds several prestigious awards, including fellowships and research chairs that underscore her contributions to the field of structural biology and microbiology. Additionally, she engages in supervising graduate and undergraduate research, fostering the next generation of scientists in this important area of study.
Department of Sociology