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Mandana Arbab is an Assistant Professor at Boston Children’s Hospital and Harvard Medical School, working in the Department of Neurology. Her research focuses on developing gene-based therapeutics for genetic neurological diseases, including neurodegenerative diseases and motor neuron diseases. She utilizes genome editing tools to modify genetic sequences related to these conditions. Her expertise includes CRISPR-based genome editing techniques, particularly the use of Cas nucleases and base editors. With these tools, she aims to empirically evaluate and improve genome editing strategies to understand and treat genetic abnormalities causing these diseases. Her work involves designing genome editing approaches for animal models to investigate the impact of genetic mutations and developing novel therapeutics.
Boston Children's Hospital • Boston, MA
Conducts research on gene-based therapeutics for genetic neurological diseases.
Administered by the Division of Medical Sciences (DMS). GRE is not required and will not be considered for BBS, Immunology, and Neuroscience.