Dr. Manoj Pillai

Biography

Manoj M Pillai, MBBS is an Associate Professor at the Yale School of Medicine specializing in Hematology. He is also a physician-scientist with a focus on hematopoiesis and the cellular microenvironment, particularly studying RNA mechanisms and their significance in both normal bone marrow physiology and altered clonal myeloid disorders. His work involves the use of genome-wide transcriptomic techniques and examines the role of small RNAs and long non-coding RNAs in regulating hematopoietic stem progenitor cells (HSPCs). Dr. Pillai is actively involved in patient care as a practicing hematologist, managing patients in leukemia and stem cell transplant units at Yale New Haven Hospital. His research interests include the biology of spliceosome mutations in Myelodysplastic Syndromes, and the function of Musashi proteins in aggressive myeloid leukemia, specifically related to chemotherapy resistance. He collaborates frequently with other researchers and has published numerous articles in the field, contributing to a better understanding of blood disorders and the development of targeted therapies for cancer treatment.

Research Interests