Dr. Manolis Roulis

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Biography

Dr. Manolis Roulis leads the research at Roulis Lab at the Perelman School of Medicine. His lab focuses on the tissue microenvironment and its role in diseases, particularly understanding the complex interactions among resident cell types, the immune system, and microbiota. The lab investigates how these interactions maintain homeostasis in mucosal barrier tissues and what happens when this balance is disrupted, leading to inflammation, fibrosis, and neoplasia. A particular emphasis is placed on studying various types of fibroblasts within the intestinal mucosa, each with unique transcriptional programs and functions. The lab is dedicated to uncovering the physiology of these fibroblasts in both health and disease, an area that remains largely unexplored.

Research Interests

Experience

Principal Investigator

2020-01-01 — Present

Roulis Lab • Philadelphia, PA

Leading research on tissue microenvironment and its implications in various diseases.

Requirements for University of Pennsylvania

Doctorate Program
Requirements
GPA Requirement
Required:3.6
GRE General
Verbal
Required:162
Quantitative
Required:162
Overall
Required:162
GMAT
Total Score
Required:728
Overall
Required:728
TOEFL
Total
Required:115
Prerequisites
Bachelor's degree or equivalent Strong quantitative background
Application Checklist
  • Academic Transcripts
  • Letters of Recommendation (2-3)
  • Resume/CV
  • Statement of Purpose
  • Essays
Specialization Notes

Wharton Doctoral programs cover fields like Finance, Marketing, Management, and Operations, Information and Decisions.