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Manolis Roulis, Ph.D., is an Assistant Professor in the Department of Pathology and Laboratory Medicine at the Perelman School of Medicine at the University of Pennsylvania. With a background in Immunology and a Ph.D. from the University of Ioannina, he focuses on the biology of intestinal fibroblasts and their role in maintaining the homeostasis of mucosal barrier tissues. His research aims to explore the balance between tissue integrity and the onset of chronic inflammatory and fibrotic processes that can lead to irreversible changes in tissue architecture. Roulis integrates single cell studies and functional analyses using mouse models and human organoid systems to uncover the mechanisms by which fibroblasts influence intestinal inflammation and tumorigenesis. His laboratory works to understand the complex interactions among resident cell types, the immune system, and the microbiota, addressing critical gaps in knowledge regarding how these elements contribute to health and disease.
Perelman School of Medicine, University of Pennsylvania • Philadelphia, PA
Researcher and educator in the field of Pathology and Laboratory Medicine.
Wharton Doctoral programs cover fields like Finance, Marketing, Management, and Operations, Information and Decisions.