Dr. Marcello Distasio

Biography

Marcello DiStasio is a neuropathologist researcher specializing in neuroimmunology, with a background in electrophysiology and biomedical engineering. His research focuses on the diseases of the central nervous system and motor system diseases, particularly cancer. He works on advancing techniques in computational pathology to better understand and diagnose diseases. His research applies machine learning, image analysis, and statistics to histology and genomic data to characterize and classify tumors. DiStasio is developing software to analyze histologic images from routine clinical evaluations of tissue and employs statistical machine learning techniques to identify patterns in cell placement and morphology that correspond to genetic profiles of tissues. He believes that simultaneous genotypic and phenotypic characterization of tumors is crucial for deeper understanding of neurobiology, neuropathology, and cancer immunology, aiding in the identification of key elements in CNS microenvironments that influence pathologic processes affecting the brain, retina, spinal cord, and peripheral nervous system.

Research Interests