Dr. Marcelo Coba

Biography

Marcelo Pablo Coba is an Associate Professor in the Department of Psychiatry & Behavioral Sciences at the Keck School of Medicine of the University of Southern California. His research focuses on neurodevelopmental and neurodegenerative psychiatric diseases, particularly complex brain disorders. Coba’s work revolves around understanding the genetic underpinnings that contribute to these conditions. He investigates how specific genes affect the pathology and susceptibility to disorders by studying synaptic proteins involved in synaptic plasticity and their complex interactions within the post-synaptic density. His long-term goal is to elucidate candidate risk factors and how functionally integrated mutations impact developmental signaling networks. He employs a systems biology approach, utilizing cutting-edge proteomic assays alongside mouse genetics and computational biology to explore these interactions, aiming to establish network maps that could help stratify patients based on their genetic backgrounds and associated symptoms.

Research Interests

Experience