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Marcos Simoes-Costa is an Associate Professor in the Department of Systems Biology and the Department of Pathology at Harvard Medical School. His research focuses on decoding the molecular programs that orchestrate cell differentiation during vertebrate embryonic development. Using functional genomics, he characterizes the gene regulatory circuits that control cell state transitions. Particularly interested in the networks of regulatory genes that operate in the early embryo, his work aims to recapitulate developmental programs in vitro to engineer cell types for repair and regeneration. A primary model choice is the neural crest, a stem cell population that plays a crucial role in the genesis of the vertebrate body plan. Neural crest cells emerge from the developing central nervous system and give rise to intricate structures such as the craniofacial skeleton and peripheral ganglia. His approach integrates multiple layers of regulation that work together to control cell identity and behavior, utilizing the neural crest system as an essential developmental model.
Harvard Medical School • Boston, MA, US
Leading research on embryonic development and gene regulatory networks.
Administered by the Division of Medical Sciences (DMS). GRE is not required and will not be considered for BBS, Immunology, and Neuroscience.