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Marieke van der Schaaf specializes in clinical neuropsychology and cognitive neuroscience. Her research aims to bridge the gap between cognitive neurosciences, medical sciences, and clinical practice, striving to increase the mechanistic understanding of the neural mechanisms underlying motivational deficits and fatigue in medical diseases. Ultimately, her work focuses on improving pharmacological and behavioral treatments. Van der Schaaf specifically studies the dissociable effects of biological and psychological factors on mental well-being and aims to explore the role of immune-brain interactions in the emergence and maintenance of motivational symptoms in diseases. Her research combines immune and pharmacological manipulations with neuroimaging techniques, blood sampling, behavioral assessments (such as effort-based decision making), and questionnaires in healthy populations as well as longitudinal patient studies.
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