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Marika Charalambous has focused her research on the relationship between epigenetic gene dosage control and developmental physiology. Her work utilizes imprinted genes in mouse experimental models to understand the effects of epigenetic modulation on dosage-sensitive genes, which have significant consequences for prenatal growth and development. During her postdoctoral work, she investigated the roles of imprinted genes on mouse chromosome 12 and their impact on brown adipose tissue development and placental growth in collaboration with the Ferguson-Smith lab at the University of Cambridge and the Ward lab at the University of Bath. She also has a background in metabolic medicine, linking prenatal development to lifelong metabolic health. Appointed Early Careers Fellow at the Centre for Endocrinology at Queen Mary University of London in 2013, she became a Senior Lecturer in 2015 and joined the Department of Medical and Molecular Genetics at King’s College London in 2017, coordinating research into maternal liver physiology and nutrient supply to developing conceptuses.
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