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Mariko Bennett, MD, PhD, is an Assistant Professor in the Department of Neurology at the Perelman School of Medicine at the University of Pennsylvania. She specializes in pediatric neurology, focusing on genetic and acquired neuroimmunological disorders such as leukodystrophies and genetic leukoencephalopathies. Dr. Bennett has developed a comprehensive platform for studying microglia—the brain's tissue-resident macrophages—encompassing identification, culture, sequencing, transplantation, and in vivo manipulation of these cells. Her research aims to understand how microglia contribute to the development of diseases and to inform therapeutic approaches. She has a keen interest in bridging basic science and clinical practice to unlock new therapeutic avenues for pediatric neuroinflammatory disorders, utilizing next-generation sequencing and human organoid models. Her notable publications include studies on microglial replacement and neurodevelopmental neurodegeneration. Dr. Bennett has earned her MD/PhD from Stanford University and previously completed her BS in Behavioral Neuroscience, graduating summa cum laude from Northeastern University.
Perelman School of Medicine at the University of Pennsylvania • Philadelphia, PA
Assistant Professor in the Department of Neurology, specializing in pediatric neurology and neuroinflammatory disorders.
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