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Marisa S. Bartolomei, Ph.D., is a Perelman Professor in the Department of Cell Developmental Biology at the University of Pennsylvania's Perelman School of Medicine. Her research focuses on genomic imprinting and X inactivation in mice, which are vital processes for normal mammalian development. The lab studies how the expression of genes from maternal and paternal alleles is unequal due to genomic imprinting, which has implications for understanding genetic regulation and the effects of environmental factors on gene expression. Some of the significant research areas include analyzing DNA methylation, the mechanisms of X inactivation related to dosage compensation in female mammals, and the impact of Assisted Reproductive Technologies on genomic imprinting. Dr. Bartolomei's lab explores numerous projects aimed at understanding both the fundamental aspects of gene regulation and the environmental influences that might perturb these essential biological processes.
Perelman School of Medicine, University of Pennsylvania • Philadelphia, PA
Teaching and conducting research in the Department of Cell Developmental Biology.
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