Dr. Marius Locke

Biography

Marius Locke is an Associate Professor in the Department of Kinesiology and Physical Education at the University of Toronto, specializing in muscle damage and the cellular responses associated with it. His research focuses on the regulation, expression, and protective effects of stress and heat shock proteins (HSPs) in striated muscle. Locke investigates how these proteins are synthesized rapidly in response to stressful conditions, which can help protect cells and tissues during episodes of stress. His current research examines the relationship between HSP content and the ability to protect skeletal muscle from damage caused by eccentric muscle contractions, as well as the inflammatory response that follows. He utilizes various mammalian models, including those experiencing diabetes, hypertrophy, exercise, and temperature stressors, to better understand the role of HSPs in muscle protection.

Research Interests

Experience