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Mark Applebaum is an Associate Professor at the University of Chicago in the Biological Sciences Division. He specializes in Pediatric Oncology with a particular focus on adolescent and young adult cancer care, specifically neuroblastoma, sarcomas, and solid tumors. As a translational physician-scientist, he is dedicated to harnessing genomics and big data to advance treatments for children with neuroblastoma. His research bridges the fields of epigenetics, genomics, and cancer biology to identify novel risk classifiers and therapeutic targets for patients with aggressive neuroblastoma. His laboratory investigates the effects of low-oxygen environments on tumors and how these conditions contribute to cancer cell resistance against standard therapies. By identifying pivotal genes and cellular pathways responsible for these changes, Dr. Applebaum aims to uncover new therapeutic options for children battling neuroblastoma. His research is proudly supported by the National Cancer Institute and various foundations, showcasing his active role in advancing pediatric cancer treatment.
Department of Philosophy