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Dr. Mark Applebaum is an Associate Professor in the Department of Pediatrics at the University of Chicago, with a focus on pediatric oncology. He specializes in adolescent and young adult cancer care, specifically neuroblastoma, sarcomas, and solid tumors. As a translational physician-scientist, Dr. Applebaum employs genomics and big data to improve treatment methods for children suffering from neuroblastoma. His research bridges the fields of epigenetics, genomics, and cancer biology, aimed at identifying novel risk classifiers and therapeutic targets for aggressive neuroblastoma. His lab investigates the low-oxygen environment of tumors, which can induce epigenetic changes that make cancer cells resistant to traditional therapies. The ultimate goal of his research is to discover genetic pathways that lead to new therapeutic avenues. Supported by various funding agencies including the National Cancer Institute and the Conquer Cancer Foundation, Dr. Applebaum has received multiple accolades from organizations such as the American Society of Clinical Oncology and the American Association for Cancer Researchers.
Department of Philosophy