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Mark Fishman is a Professor in the Department of Stem Cell and Regenerative Biology at Harvard University. His research focuses on understanding the circuitry function of individual nerve cells, particularly in the context of the heart. His studies utilize zebrafish models to explore how nerve cells connect to heart muscle pacemaker cells and how these interactions influence cardiac physiology and responses to environmental stressors such as hypoxia. Collaboratively, Fishman's lab works with other experts to employ advanced techniques like single cell transcriptional analysis, electron microscopy, and optogenetics to uncover the detailed functions of these individual nerve cells. His work addresses critical questions in dysautonomia, a disorder characterized by malfunctions in autonomic nervous system signaling, and aims to elucidate the mechanisms underlying various cardiac conditions.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).