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Mark Goulian is the Charles William L. Day Distinguished Professor in the Department of Physics and Astronomy at the University of Pennsylvania. His research primarily focuses on biophysics and condensed matter, particularly mechanisms by which bacteria adapt to changes in their environment. His lab investigates biochemical circuits that enable Escherichia coli and related bacteria to sense and respond to intra- and extracellular signals, with a particular interest in how these circuits evolve and interact with cellular pathways. Current research areas include antimicrobial peptide resistance, adaptation to variations in oxygen availability, and commensal colonization in animal hosts. With an educational background that includes a Ph.D. from Harvard University, Goulian has held various academic positions at the University of Pennsylvania since 2000, moving from Assistant Professor to his current distinguished role.
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