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Mark Haskins is a faculty member at the Perelman School of Medicine at the University of Pennsylvania, specializing in research related to large animal models of human genetic diseases. His expertise encompasses the discovery and characterization of therapies for various conditions, particularly lysosomal storage disorders. Haskins has contributed significantly to understanding metabolic diseases caused by deficient enzyme activities through experimental gene therapies aimed at both cats and dogs affected by mucopolysaccharidoses and other genetic conditions. Some of these experiments include administering recombinant human alpha-L-iduronidase and using retroviral vectors for gene therapy. His work illustrates the clinical phenotypes of lysosomal storage disorders in animals and children, promoting advancements in gene therapy applications.
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