Professor Dr. Mark Hogarth

Biography

Professor Hogarth's research focuses on the immune system's role in intractable human diseases, emphasizing autoimmunity and inflammation. His work investigates the fundamental roles of immune cells, receptors, and antibodies, aiming to manipulate these elements for the treatment of human diseases. The research program encompasses basic, applied, and translational projects, which have significantly contributed to understanding immune function and the subsequent development of potential biological therapeutics for inflammation and cancer. Projects examine human receptor gene polymorphisms and protein biomarkers associated with disease, leading to the creation of new monoclonal antibodies and engineered receptor proteins. His extensive studies cover the biochemistry and structure-function relationships of key genes and proteins in immunity, particularly cell surface molecules. Recent findings have defined antibody-based effector systems related to tissue inflammation and autoimmune diseases. His work has implications for various conditions including leukemia, breast and colon cancers, and autoimmune diseases like lupus and rheumatoid arthritis. Professor Hogarth has considerable experience in translational research and technology transfer, contributing to the establishment of companies focused on biomarkers and immunological diagnostics. He has held leadership roles in notable research institutions and is a recipient of prestigious awards, underscoring his significance in the field of immunological research.

Research Interests

Experience

Awards