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Professor Mark Sleeman brings a unique wealth of experience from Monash University, having arrived in July 2011 after spending 18 years in the United States, primarily with Regeneron Pharmaceuticals Inc. where he served as Head of Metabolic Research. In this role, he oversaw discovery research and therapeutic development for various metabolic diseases, including leading therapeutics through Phase-III clinical trials. His team developed breakthrough treatments for high cholesterol in humans. Currently, he is assembling the Physiological Genomics Group to research metabolic diseases, with an emphasis on integrating basic science with therapeutic development. His research interests include understanding mechanisms associated with type 2 diabetes and obesity, and he identifies significant gaps in validated targets for therapeutics in these areas. His work is rooted in a commitment to bridge the gap between basic and clinical sciences, aiming to improve therapeutic outcomes through innovative approaches. His expertise encompasses various aspects of diabetes, lipid disorders, therapeutic antibodies, and biotechnology, particularly studying insulin resistance and inflammatory liver diseases such as non-alcoholic steatohepatitis (NASH).
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