Generate a tailored SOP for Dr. Marsha Rosner. Improve your application with a focused, well-structured draft.
Marsha Rosner is the Charles B. Huggins Distinguished Service Professor at the University of Chicago, specializing in Cancer Biology. Her research interests include the mechanisms of cancer progression, with a particular focus on triple-negative breast cancer—a type that lacks targeted therapies. The laboratory employs systems-level approaches such as activity-based proteomics, RNA sequencing, and mass spectrometry, alongside mouse model methodologies, to identify key regulators of tumor growth and metastasis. Recent studies have indicated a connection between the tumor microenvironment and the metabolic programming of tumor-associated macrophages, suggesting that extracellular vesicles secreted by tumor cells can reprogram surrounding cells to exhibit a pro-metastatic phenotype. By correlating omics-generated data with clinical patient data, she has helped to identify novel signaling modules that could be used to predict metastatic potential and guide therapeutic interventions.
Department of Philosophy