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Mary C. Andorfer is a professor in the Department of Chemistry at Michigan State University. Her research focuses on enzyme engineering and the development of sustainable biocatalysts for producing value-added chemicals from inexpensive and abundant feedstocks, including CO2 and hydrocarbons. Her lab investigates the mechanisms by which anaerobic microbes can activate components of crude oil, aiming to understand and utilize these processes for bioremediation in hydrocarbon-polluted environments. The Andorfer lab employs a range of advanced methods, including directed evolution, structural biology techniques such as cryo-electron microscopy (cryo-EM), and various biochemical assays to engineer enzymes with selective catalytic properties. Key projects involve understanding enzyme functions that can transform complex organic molecules and resolving novel protein structures to inform subsequent protein engineering efforts.
Michigan State University • East Lansing, MI
Conducting research in enzyme engineering and teaching in the Department of Chemistry.
Department of Psychology