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Mary Eileen Dolan is a Professor in the Biological Sciences Division at the University of Chicago. Her research primarily focuses on improving the quality of life for cancer patients by identifying genetic variants associated with the risk of severe, persistent toxicities related to chemotherapy, including peripheral neuropathy and ototoxicity. Specifically, her lab conducts clinical genome-wide association studies (GWAS) to explore the genetic foundations of these adverse effects. Dolan's work is notable for integrating large datasets encompassing genetic variation and gene expression to reveal insights into drug-induced pharmacologic traits. She has developed induced pluripotent stem cell-derived neuronal models that aid in understanding the genetic contributions to chemotherapeutic-induced neuropathy. Additionally, her innovative use of machine learning techniques aims to develop predictive models that identify patients at the highest risk for severe toxicities arising from chemotherapy. Throughout her career, Dolan has received numerous awards for her contributions to cancer research, mentorship, and inclusion within the scientific community.
Department of Philosophy