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Matthew Crump is a Professor of NMR Structural Biology at the University of Bristol, where he focuses on understanding protein structure and function through nuclear magnetic resonance (NMR) spectroscopy. His research has significant implications in the fields of cancer biology and antibiotic drug design, emphasizing the pivotal role of structural biology in addressing contemporary health issues. In recent projects, he has contributed to elucidating the solution NMR structure of the insulin growth factor receptor 2, which marks a milestone in therapeutic receptor development for cancer treatment. His laboratory employs NMR screening to investigate potential small ligands with pharmaceutical interest, supported by research funding from UCB and other agencies. Crump's work also integrates X-ray crystallography for larger protein structure determinations, with multiple collaborative projects in progress. He supervises research at the EPSRC Centre for Doctoral Training in Chemical Synthesis, emphasizing innovative techniques for elucidating natural product biosynthesis.
University of Bristol • Bristol, ENG, GB
Leading research on protein structure and function using nuclear magnetic resonance spectroscopy.
Department of Physics research themes include Astrophysics, Materials and Devices, Particle Physics, and Quantum and Soft Matter.