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Matthew Kirchner is an Assistant Professor at Texas A&M University, specializing in Medical Physiology. His primary research focuses on neurophysiology, particularly the functions of oxytocin (OT) and vasopressin (VP) magnocellular neurons in the supraoptic nucleus. Kirchner's studies delve into the mechanisms of central neuroendocrine information processing, particularly how these neurons project their axons to the posterior pituitary for the release of OT and VP into the bloodstream, impacting various peripheral targets. His research also investigates the intrinsic excitability of these neurons, especially regarding calcium-dependent potassium channels and their role in generating afterhyperpolarization (AHP) currents that affect neuronal spiking. A significant aspect of his work involves examining the slow AHP (sAHP) and its modulation. Kirchner's lab is dedicated to understanding the somatodendritic release of neuropeptides and its implications for population activity in the hypothalamus. Additionally, his research addresses heart failure, characterized by increased circulating VP and hyperexcitable VP neurons, which may lead to detrimental effects such as excessive water retention and hyponatremia.
Texas A&M University • Bryan, TX
Teaching and conducting research in Medical Physiology, with a focus on neurophysiology and hormone function.
Department: Department of Communication and Journalism. Ph.D. program only currently admitting. GRE is test-optional.