Professor Dr. Matthew Moulton

Biography

Matthew Moulton joined the Texas A&M University Department of Biology as an Assistant Professor in 2024. His research interests lie in exploring the molecular mechanisms of genes associated with neurological diseases, focusing particularly on Alzheimer's disease. He utilizes the genetic model organism Drosophila melanogaster (fruit fly) to understand the impacts of disease-associated genetic variations. Moulton's lab employs genetic technologies to swap human DNA sequences into the fly genome, which allows for probing the effects of specific variants on organismal function. His research emphasizes the importance of proper neuronal function supported by glial cells and investigates the effects of oxidative stress on neurons, which is influenced by age and disease. By analyzing glial lipid droplet formation and its relation to neurodegeneration through humanized fly models, Moulton aims to identify risk genes and molecular functions that contribute to complex neurological diseases, thus paving the way for potential therapeutic interventions.

Research Interests