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Matthew S. Sachs joined the Department of Biology at Texas A&M University in 2007, where he serves as a Professor. His research interests are primarily centered around understanding the mechanisms by which upstream open reading frames (uORFs) in mRNA transcripts control gene expression. His lab is currently focused on the function of uORF-encoded fungal arginine attenuator peptide (AAP) and its influence on ribosomal movement and mRNA stability in different organisms including fungi and plants. He has been associated with major funded projects from the National Institutes of Health and the National Science Foundation and has held various leadership roles in scientific communities, including chairing committees and co-chairing conferences. His work includes significant contributions to the understanding of uORF in gene expression regulation, particularly how AAP affects the stability of mRNA through ribosome stalling mechanisms under varying arginine conditions. In addition, his lab engages in large-scale genomic analyses and the curation of genome data for Neurospora crassa, collaborating with institutes such as the Broad Institute. His educational background includes a Ph.D. in Biology from the Massachusetts Institute of Technology and previous faculty appointment at Oregon Health Science University.
Department: Department of Communication and Journalism. Ph.D. program only currently admitting. GRE is test-optional.