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Matthew J. Smith is an Associate Professor at the University of Montreal, specializing in Health Sciences and Medical Sciences. His primary research interests lie in cancer biology, structural biology, and cell signaling. He aims to integrate modern experimental approaches to understand abnormal cancer signaling at both systemic and mechanical levels. By exploring the correlations between genetic mutations, altered protein structures, and disturbed protein networks, his team investigates the processes that lead to cell transformation and metastatic dissemination. Key research themes include RAS GTPases, MAPK signaling pathways, microtubule cytoskeleton dynamics, and various structural biology techniques such as Nuclear Magnetic Resonance (NMR) spectroscopy and X-ray crystallography. He teaches courses on protein biochemistry and supervises graduate students in molecular biology and biomedical engineering. Matthew J. Smith has garnered various funding sources for his innovative research in cancer signaling and is actively involved in projects aimed at elucidating molecular mechanisms for targeting RAS effector pathways, which could lead to new therapeutic strategies against human cancers.
University of Montreal • Montreal, QC
Teaches and supervises graduate courses in molecular biology, focusing on cancer signaling mechanisms.
Most programs require French B2 level; specific departments may require C1 or C2.