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Matthew Wilson received his Ph.D. in Computational Neural Systems from the California Institute of Technology and completed his postdoctoral training at the University of Arizona. In 1994, he joined the faculty of the Department of Brain and Cognitive Sciences and the Picower Institute for Learning and Memory at MIT. His research laboratory focuses on the neural processes in the hippocampus and neocortex that enable memories to form and persist for long periods. Using techniques that allow the simultaneous recording of activity from hundreds of individual neurons across multiple brain regions in freely behaving animals, Wilson's work employs genetic, pharmacological, and behavioral manipulations to gain a mechanistic understanding of how animals learn and remember. A significant area of investigation in his lab is the reactivation of sequential activity in neural ensembles during waking and sleep states. The cells in the hippocampus represent specific locations, using firing patterns to reconstruct movement trajectories that are