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Megan Sykes is a prominent researcher specializing in transplantation, particularly hematopoietic cell transplantation and organ allograft tolerance. She has published over 440 scientific works, including papers and book chapters, focusing on novel strategies for achieving graft-versus-tumor effects. Dr. Sykes has developed approaches for non-myeloablative haploidentical hematopoietic cell transplantation, contributing to clinical trials that enhance safety and efficacy and induce organ allograft tolerance. Her work includes pioneering minimal conditioning approaches using hematopoietic cell transplantation to achieve tolerance in both allografts and xenografts. Furthermore, she has developed innovative “humanized mouse” models for personalized analysis of human immune disorders and therapies. A past president of the International Xenotransplantation Association, Dr. Sykes has held several leadership roles within various established medical organizations and received numerous awards, including the 2018 Medawar Prize. With extensive experience at Columbia University, she directs the Columbia Center for Translational Immunology, fostering multidisciplinary research in transplantation and immunology.
Columbia University • New York, NY
Leading research and academic programs in Microbiology, Immunology, and Surgical Sciences.
Department of Anthropology (GSAS)