Dr. Mehmet Sofuoglu

Biography

Mehmet Sofuoglu is a Professor of Psychiatry at Yale School of Medicine, where he focuses his research on the development of novel treatments for substance use disorders that co-occur with psychiatric disorders. He conducts Phase 1 human laboratory studies and outpatient clinical trials to test the efficacy and potential of new treatments. Dr. Sofuoglu's research interests include tobacco regulatory science, particularly studying the impact of nicotine flavors on the appeal and abuse potential of tobacco products. He has developed a unique intravenous nicotine self-administration model that allows for the examination of the rewarding and aversive effects of nicotine among male and female smokers. Recent studies include examining the reinforcing threshold of this model, individual factors influencing the effects of nicotine, the impact of menthol flavors, the potential efficacy of cognitive enhancers for treating substance use disorders, and the role of progesterone as a preventive treatment for relapse in women with substance use disorders.

Research Interests