Dr. Michael Cleary

Biography

Michael Cleary is the Lindhard Family Professor of Pediatric Cancer Biology in the Department of Pathology at Stanford University School of Medicine, where he has been a major contributor to research in hematopoietic cell growth and differentiation, as well as its disruption in neoplastic transformation, particularly in leukemias and lymphomas. His research emphasizes developmental pathways, studying various experimental systems such as molecular biology techniques and transgenic knockout mice. His interests include characterizing novel families of oncoproteins, specifically Pbx and Meis proteins, which regulate DNA binding properties of Hox proteins and contribute to the specificity of Hox function during development. He also investigates the role of chromatin structure in gene regulation, especially in hematopoietic cells. As part of his work, he strives to develop new diagnostic procedures to detect and monitor leukemia in patients utilizing molecular genetic abnormalities of malignant cells. Dr. Cleary's impactful research and teaching continue to shape the understanding and treatment of pediatric cancers, reflecting his commitment to advancing medical science through innovative research methodologies.

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