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Michael Granato is a Professor in the Department of Cell Developmental Biology at the Perelman School of Medicine, University of Pennsylvania. He holds a Ph.D. from the University Tübingen, where his research focused on the molecular analysis of organ-specific gene functions in C. elegans. His lab employs zebrafish as a model organism to investigate the molecular and cellular mechanisms underlying axon regeneration in both the peripheral and central nervous systems, as well as the neurobiological underpinnings of autism and schizophrenia-related behaviors. With a strong emphasis on live-cell imaging and molecular genetic tools, the Granato lab explores fundamental questions across Neuroscience, particularly how signaling pathways influence axonal development and connectivity. His work is characterized by innovative approaches such as RNA sequencing, CRISPR/Cas9 genome editing, and whole-brain activity imaging to capture the dynamics of axon-glia interactions during neural regeneration. Granato's research has notable implications for understanding human health conditions related to neural injuries and developmental disorders.
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