Dr. Michal Caspi Tal

Professor

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Biography

Michal Caspi Tal, PhD, is an immunoengineer serving as a Principal Scientist at the Massachusetts Institute of Technology (MIT). She leads the Tal Research Group in the Department of Biological Engineering and is the Associate Scientific Director of the Center for Gynepathology Research. Her research focuses on identifying connections between infections and chronic diseases, particularly developing predictive diagnostics and generating actionable information for providers to improve diagnosis and treatment of invisible chronic diseases. Her work has highlighted the similarities between tick-borne diseases and chronic inflammatory diseases, emphasizing the importance of sex differences in responses to infections. Michal received her PhD in Immunobiology from Yale University, where she researched immune responses to viruses and the impacts of aging under the mentorship of Dr. Akiko Iwasaki. Following her doctorate, she completed postdoctoral training in the lab of Irving Weissman at Stanford University, where she led a team studying immunomodulatory mechanisms affecting immune clearance of infectious diseases, especially Lyme disease. Michal has been recognized with NIH NIAID F31 and F32 fellowships, as well as the Emerging Leader Award from the Bay Area Lyme Foundation.

Research Interests

Experience

Principal Scientist

2021-01-01 — Present

Massachusetts Institute of Technology • Cambridge, MA

Leading research in immunoengineering and diagnostics related to chronic diseases.

Associate Scientific Director

2021-01-01 — Present

MIT Center for Gynepathology Research • Cambridge, MA

Overseeing scientific endeavors related to gynepathology research.

Instructor

2019-01-01 — 2020-12-31

Stanford University • Stanford, CA

Teaching and conducting research focused on immunomodulatory mechanisms and infectious diseases.

Awards

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Emerging Leader Award

2020-01-01