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Michela Locci is an Associate Professor in the Department of Microbiology at the Perelman School of Medicine, University of Pennsylvania. She completed her Masters in Biotechnology at the University of Bologna in 2005 and obtained her Ph.D. in Immunology Applied Biotechnology from Tor Vergata University in 2010. Her research focuses on the production of high-affinity antibodies and the role of T follicular helper cells in B cell responses. Her lab employs a multidisciplinary approach that combines cellular, molecular immunology, and transcriptomics to study Tfh cell differentiation and their functionality within germinal centers. She aims to uncover novel regulators of Tfh differentiation using high-throughput screening methods. Locci's work has revealed significant insights into the mechanisms governing human Tfh cell behavior and their capacity to provide help to B cells, highlighting the diversity within Tfh cell populations. Her team is also dedicated to mentoring the next generation of scientists, welcoming highly motivated undergraduate and graduate students, as well as postdoctoral fellows.
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