Dr. Micheline Piquette Miller

Biography

Micheline Piquette-Miller’s research focuses on understanding the regulation of drug transport proteins in the placenta. Her lab investigates the influence of disease and environmental factors on the regulation of transporter proteins and maternal-fetal health. The lab studies how drug transport proteins regulate the entry of drugs into tissues such as the kidney, liver, and blood-brain barrier. These transporters are critical for transferring nutrients and drugs from mother to fetus and their function is crucial for fetal exposure to potentially harmful substances from the mother's circulation. With a specific focus on maternal diseases that may affect transporter proteins, Piquette-Miller's lab uses in vitro cell culture and experimental animal models to explore the ABC and SLC transporters involved in the passage of drugs, hormones, and nutrients. Her lab collaborates with clinicians at various hospitals to conduct translational research, including human tissue studies, to optimize therapeutic choices and treatment guidelines for conditions such as ovarian cancer. Through her work, Piquette-Miller seeks to improve the understanding of children’s exposures to drugs that pass through the placental barrier and enhance safety in medication use during pregnancy.

Research Interests

Experience

Awards