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Michelle Hook is an Associate Professor at Texas A&M University, specializing in the field of Neuroscience and Experimental Therapeutics. Her research focuses on understanding the effects of opioids on recovery from spinal cord injury (SCI) and the associated psychological implications. Dr. Hook has demonstrated that morphine, a commonly used analgesic in cases of acute SCI, may adversely affect locomotor recovery and general health, contrary to its intended therapeutic effects. She explores the molecular mechanisms behind these adverse outcomes, particularly the role of kappa-opioid receptors. Additionally, Dr. Hook's research addresses the high incidence of depression in patients suffering from SCI, investigating physiological changes that accompany depression-like behaviors in rat models of injury. She is dedicated to identifying strategies that could mitigate cognitive deficits associated with depression stemming from SCI, including examining gut health. Another significant aspect of her work involves studying bone loss due to SCI, focusing on the underlying changes in the bone marrow niche and their implications for osteoblast and osteoclast activity. Through her innovative research, Dr. Hook aims to enhance understanding and develop effective therapies that improve recovery and quality of life for individuals with SCI.
Department: Department of Communication and Journalism. Ph.D. program only currently admitting. GRE is test-optional.