Dr. Michelle Krogsgaard

Biography

Michelle Krogsgaard is an Associate Professor at the Perlmutter Cancer Center, where she focuses on T-cell recognition sensitivity and its implications in cancer immunology and autoimmunity. Her research laboratory employs innovative biophysical methods like surface plasmon resonance, X-ray crystallography, and nuclear magnetic resonance spectroscopy to understand the interplay between molecular and cellular events contributing to T-cell sensitivity to self and cancer antigens. This interdisciplinary approach aims to elucidate the signaling pathways involved in T-cell activation and to develop pharmacological strategies that enhance T-cell function for improving immunotherapy outcomes. Dr. Krogsgaard's work is crucial for increasing T-cell sensitivity in cancer patients while reducing it in individuals with autoimmune diseases. She has received support from notable organizations including the Pew Trust and the Cancer Research Institute, and has made significant contributions to understanding T-cell biology and therapeutic development.

Research Interests