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Mikhail G. Shapiro is a Professor of Chemical Engineering and an HHMI Investigator at Caltech. He earned his PhD from the Massachusetts Institute of Technology in 2008 and a BSc from Brown University in 2004. His research focuses on developing technologies to control cellular function in vivo through non-invasive techniques, particularly using ultrasound. His lab has innovated acoustic reporter genes to visualize tumor behavior in mouse models and created thermal bioswitches to control immune cell activity with mild hyperthermia. Shapiro's work on ultrasound-enabled therapies aims to improve cancer treatment by enabling precise control of therapeutic cell activity and enhancing the effectiveness of immunotherapy against solid tumors. He has published significant research findings in prestigious journals, contributing to advancements in biomedical engineering and therapeutic techniques.
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