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Min Dong is an Associate Professor at Boston Children's Hospital working within the Department of Biological and Biomedical Sciences. His research focuses on microbial toxins and bacterial pathogenesis affecting humans, animals, and insects. With a multidisciplinary team, Dr. Dong explores innovative therapeutic approaches inspired by microbial proteins to address genetic diseases, cancer, pain, and neurological disorders. His notable achievements include significant publications in high-impact journals, where he reported on the identification of receptors for C. difficile toxins using genome-wide CRISPR-Cas9 screening, as well as novel bacterial toxins. His ongoing projects investigate the mechanisms of bacterial toxins, host-microbe interactions, and the application of protein engineering to develop cutting-edge therapeutic toxins targeted at chronic diseases and emerging pathogens. He employs advanced techniques in microbiology, structural biology, cell biology, and neurobiology to deepen our understanding in these areas.
Boston Children's Hospital • Boston, MA
An academic role focusing on the interaction between microbial toxins and host biology, along with the development of therapeutic strategies.
Administered by the Harvard Kenneth C. Griffin Graduate School of Arts and Sciences (GSAS).