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Mindong Ren is a Research Associate Professor in the Department of Anesthesiology at NYU Grossman School of Medicine. His research focuses on the role of cardiolipin, the signature phospholipid of mitochondrial membranes, in health and disease. He investigates how cardiolipin interacts with important mitochondrial proteins and stabilizes the assembly of respiratory complexes. His work emphasizes the significance of cardiolipin in oxidative phosphorylation and its implications in pathological conditions such as ischemia/reperfusion injury, heart failure, and diabetic cardiomyopathy. Currently, he is studying Barth syndrome, an inherited cardiomyopathy caused by mutations in the tafazzin gene that lead to severe cardiolipin deficiency. This deficiency impacts the organization of ATP synthase in mitochondria and disrupts mitochondrial function. His research aims to elucidate the complex roles cardiolipin plays in various diseases and improve understanding in this area.
Open Program in Biomedical Sciences (Vilcek Institute) covers departments like Biochemistry, Pathology, Neuroscience, Microbiology, etc.