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Dr. Sarkar-Tyson completed her PhD studies at the University of Manchester, UK, followed by a post-doctoral position at the Drug Discovery Centre, University of Dundee. She worked at the Defence Science and Technology Laboratories (DSTL) in the UK as a Principal Scientist and Project Manager. She joined the University of Western Australia (UWA) in 2016 as a Le Souef Research Fellow in the School of Biomedical Sciences, where she leads the Burkholderia research group. Dr. Sarkar-Tyson has a strong interest in neglected tropical diseases and the discovery of new medical countermeasures, particularly focusing on understanding the molecular mechanisms by which bacteria cause disease. Her primary research focus is on the Gram-negative bacterium, Burkholderia pseudomallei, which causes melioidosis, a tropical disease endemic to Northern Australia and Southeast Asia. Melioidosis is estimated to occur in 45 countries worldwide, with a predicted global burden of 165,000 cases and 89,000 fatalities in the past year. Given the effective antibiotic treatment, the mortality rates for melioidosis in Northern Australia stand at 20%. B. pseudomallei is intrinsically resistant to multiple classes of antibiotics, making the development of novel medical countermeasures a high priority for her research. Additionally, she has identified virulence factors that enable B. pseudomallei to cause disease, and is currently collaborating with international partners to identify new inhibitors.
University of Western Australia • Perth
Leading research on Burkholderia and associated diseases.
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