Generate a tailored SOP for Dr. Mitchell Lewis. Improve your application with a focused, well-structured draft.
Mitchell Lewis is a faculty member at the Perelman School of Medicine, University of Pennsylvania, specializing in the field of Biomedical Research. His primary research objective is to understand how proteins respond to metabolites and regulate transcription. Over the past half-century, his work has significantly contributed to the understanding of gene regulation, focusing on the lac operon of Escherichia coli and its repressor. He has provided detailed structural information on key components of the lac operon, including determining the three-dimensional structures of the lac repressor both in its free form and when bound to operator DNA and the inducer IPTG. His lab's research aims to build a comprehensive biochemical and structural understanding of the specificity of repressor binding and the molecular basis for allosteric response. He actively investigates the cooperative binding of transcription factors and is focused on creating structural models that elucidate the mechanisms behind cooperative gene regulation.
Harvard University • Cambridge, MA
Conducted advanced research in biochemical and structural biology.
Wharton Doctoral programs cover fields like Finance, Marketing, Management, and Operations, Information and Decisions.