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Dr. Mohamed Sherif's research integrates computational neuroscience, clinical psychiatry, and brain electrophysiology. Originally from Egypt, he is a practicing psychiatrist neurologist who completed his training at Ain Shams University, Cairo, and further pursued a psychiatry residency at SUNY Downstate Medical Center, Brooklyn, NY. Dr. Sherif joined a dual Residency/Ph.D. program at SUNY Downstate Medical Center and NYU Tandon School of Engineering, where he was supervised by Dr. William Lytton. His Ph.D. research utilized biophysically-realistic computer models of the hippocampus to understand oscillatory changes in animal models of schizophrenia, investigating potential novel medication targets with mechanistic computer modeling approaches. At the VA Connecticut Healthcare System, he was awarded a Special Psychopharmacology Research fellowship, focusing on designing and conducting pharmaco-EEG clinical trials, and gained interest in using ketamine for treatment-resistant depression. He has received a VA career-development award and a grant from the Leet Patterson Foundation to explore EEG biomarkers of ketamine's antidepressant effects. At Brown University's Carney Institute, Dr. Sherif's lab employs computational techniques to elucidate microcircuit mechanisms underlying psychiatric disorders, with an emphasis on schizophrenia, Major Depressive Disorder (MDD), and Obsessive-Compulsive Disorder (OCD). The lab collaborates with other researchers to analyze EEG datasets from patients and study mechanisms of action for breakthrough treatments like ketamine and psilocybin.
Department: Department of Economics