Dr. Monique De Paepe

Biography

Monique E De Paepe is a Professor in the Department of Pathology and Laboratory Medicine at Brown University, where her research focuses on the regulation of alveolar remodeling and the development of the lung in both normal and pathological states. Particularly, she is interested in the role of apoptosis and angiogenesis in alveolarization processes. Her work aims to contribute to novel therapeutic strategies for conditions such as bronchopulmonary dysplasia, which is a chronic lung disease commonly affecting preterm infants characterized by impaired alveolar development. De Paepe employs a variety of in vitro and in vivo model systems, including transgenic mice that either overexpress or underexpress critical apoptotic molecules, to investigate the mechanisms regulating apoptosis and their impact on alveolar septation. Her recent studies also explore the mechanisms of ventilation-induced dysangiogenesis using transgenic animal models. With a strong track record of funded research, including multiple grants from the American Lung Association and the Rhode Island Foundation, she remains a prominent figure in her field.

Research Interests

Experience

Awards