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Dr. Munir Alam is a Professor in the Department of Medicine and the Department of Pathology at Duke University. He is also a member of the Duke Human Vaccine Institute. His research focuses on the biophysical properties and molecular events involved in early B cell activation, particularly in the context of HIV-1 broadly neutralizing antibody (bnAb) lineage models. His team investigates the interactions of HIV-1 envelope proteins with B cell antigen receptors to elucidate early signaling mechanisms that initiate B cell activation. Dr. Alam is involved in several NIAID-funded projects aimed at understanding antigen recognition by B cell antigen receptors and the specificity of bnAbs. His research employs high-resolution microscopy analyses to define the properties of BCR-antigen interactions, aiming to bridge quantitative biophysical measurements with B cell activation studies. He collaborates with notable researchers from various institutions to enhance vaccine design strategies against HIV-1.
Duke University • Durham, NC
Serves as a professor in the Department of Medicine and Pathology, focusing on HIV vaccine research.
Department of Biomedical Engineering (MS program)